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Key Responsibilities

- Plan and execute in vitro studies to characterize mechanisms of action, efficacy, and toxicity, including but not limited to cell viability, cytotoxicity, proliferation, apoptosis, and target engagement.
- Culture and maintain mammalian cell lines (adherent and suspension, primary cells are a plus) using aseptic technique and establish 2D and 3D models as needed.
- Perform biochemical and molecular biology assays (ELISA, qPCR/RT-qPCR, Western blot, flow cytometry, gel electrophoresis, immunofluorescence).
- Design and execute peptide studies, including handling, solubility and stability assessments, and activity assays.
- Analyze and interpret data with rigorous statistics (IC₅₀/EC₅₀ curve fitting, t-tests, ANOVA, and appropriate multiple-comparison controls) and generate precise figures and technical reports to inform project decisions.
- Collaborate cross-functionally to transfer assays, support formulation compatibility screens, align in vitro findings with in vivo pharmacology, contribute to study plans and timelines,



and present results to internal teams and leadership.
- Author protocols within the preclinical studies area, ensuring clarity, reproducibility, regulatory alignment, and version control.
- Support administrative tasks related to study execution, including sourcing and purchasing of cell lines, reagents, consumables, and instruments, as well as handling vendor communications and quotation requests.
- Research and run efficacy assays aimed at repositioning our medicine and assessing additional molecules for the treatment of diverse indications.

Qualifications

- Bachelor’s degree or MS in Biology, Biochemistry, Chemistry, Pharmacology, or a related field.
- 2+ years (industry or academic core facility) running cell-based assays, end-to-end cell culture, experiment, analysis, and report.
- Hands‑on experience with biochemistry and molecular biology techniques (ELISA, qPCR/RT‑qPCR, Western blot, flow cytometry,

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📌 Preclinical Researcher (Bogotá)
🏢 IGC PHARMA
📍 Bogotá