Main Responsibilities

- Develop and execute the local Rare Disease Medical Plan for Neurology and Metabolic portfolios, in alignment with general, regional, and Therapeutic Area strategies.
- Lead medical activities from L-18 through launch and post-launch, ensuring scientific, diagnostic, and healthcare-system readiness.
- Identify and address barriers across the rare disease patient journey: awareness, patient identification, diagnostic delay, referral to specialized centers, treatment initiation, and long-term follow-up.
- Define and execute medical strategies for prioritized centers and accounts, in partnership with Market Access, MSLs, Government Affairs, Diagnostics, and Patient Programs.
- Contribute to value propositions, health-economic initiatives, and access strategies. Support technical discussions with payers, health authorities, and policymakers on the particular challenges of rare, high-cost, and chronic therapies.
- Lead and oversee local evidence generation relevant to small populations, including registries, natural history and observational studies, RWE, publications, and outcomes research.
- Strengthen diagnostic pathways in collaboration with clinical laboratories, genetic and biomarker testing initiatives, and scientific societies.
- Translate scientific evidence and external insights into actionable recommendations for Medical Affairs, Access, account strategy, and healthcare policy.
- Identify and support innovative initiatives using AI, data, and digital solutions to improve patient identification, diagnosis, and care coordination.
- Build trusted relationships with neurologists,



metabolic and genetics specialists, pediatricians, internists, scientific societies, academic institutions, and patient organizations.
- Represent Medical Affairs externally and communicate complex scientific information clearly and appropriately to diverse audiences.
- Coach and develop MSLs and other field medical colleagues, supporting high-quality scientific engagement and execution.
- Collaborate with Medical Affairs, Market Access, Government Affairs, Regulatory, Commercial, Pharmacovigilance, Compliance, and Patient Programs.
- Ensure all activities comply with AstraZeneca policies, Medical Governance, Pharmacovigilance, GxP, Code of Conduct, and local regulations.
- Manage medical resources and budget according to strategic priorities, patient impact, and healthcare-system needs.

Key Requirements

- Medical Doctor, Pharmacist, or healthcare professional with postgraduate training in a clinical or related health sciences field.
- 5–7 years of experience in Medical Affairs within the pharmaceutical industry.
- Experience in rare diseases, neurology, metabolic or genetic diseases, or other specialty and complex chronic conditions, including supporting launches or medical strategies.
- Experience working cross-functionally with Medical Affairs,



Market Access, Government Affairs, Evidence Generation/RWE, and external stakeholders.
- Strong scientific knowledge and ability to translate evidence into strategic recommendations, including in contexts with limited data and small patient populations.
- Understanding of healthcare systems, patient pathways, diagnostic and referral barriers, and access challenges for high-cost therapies.
- Strong strategic thinking, stakeholder management, communication, influencing, and project management skills.
- Ability to work effectively in a complex, matrixed, multi-country environment and influence without authority.
- Experience working with data, digital tools, or AI in healthcare is desirable.
- Professional proficiency in English, written and spoken.
- Ability and willingness to travel according to business needs.

Preferred Qualifications

- Advanced degree such as MD, PhD, PharmD, MSc, or equivalent.
- Direct experience in rare diseases, including launch or pre-launch readiness.
- Experience in RWE, HEOR, registries, natural history studies, or outcomes research.
- Experience working with payers, health authorities, policymakers, scientific societies, or patient advocacy groups.
- Experience in patient identification, diagnostic-pathway optimization, centers of expertise, or innovative models of care.
- Previous people leadership, coaching, or matrix leadership experience.
- Experience applying AI, data analytics, or digital solutions to healthcare challenges.

Date Posted

06-nov-2026

Closing Date

14-nov-2026

📌 Medical Manager - Rare Diseases (Bogotá)
🏢 Astrazeneca
📍 Bogotá